⭐⭐⭐⭐⭐ 20,000+ Reviews | Free Returns | Expert Service & Support

Thorne - Pro-Resolving Mediators

Thorne - Pro-Resolving Mediators

60 servings per container: $1.13 / serving
$67.50 $75.00 SAVE 10%
Earn rewards — 5% back, 2700 points on this order. How rewards work
Sale price
$75.00 Regular price
Regular price
$75.00
Sale Sold out
Unit price
/per 
Shipping calculated at checkout.
NOTIFY ME WHEN IN STOCK
Stock Up & Save + Free Shipping
Buy 2 5% off $71.25 / ea
Best value Buy 3+ 10% off $67.50 / ea
*Applies to One Time Purchaes. Discount applied automatically at checkout.
Free
Returns
Fast
Shipping
Secure
Checkout
Returns & Exchange Policy
This is a pre order item. We will ship it when it comes in stock.
  • Specialized Pro-Resolving Mediators (SPMs): Oil delivering natural specialized pro-resolving mediators — enzymatically oxygenated derivatives of omega-3 EPA and DHA.
  • Active Resolution Support: SPMs are central regulators of the resolution phase of inflammation, actively stimulating removal of inflammatory exudate.*
  • Beyond Fish Oil: Different mechanism than standard omega-3s — SPMs bind specific G protein-coupled receptors to activate resolution pathways.*
  • Wound Healing Support: SPMs stimulate wound healing and expedite clearance of inflammation.*
  • Whole-Body Support: Family includes resolvins, protectins, and maresins that control duration and magnitude of inflammatory response.*
  • Third-Party Certified: Verified against label claims, confirmed free of unsafe levels of contaminants.

Thorne Pro-Resolving Mediators delivers specialized pro-resolving mediators (SPMs) — enzymatically oxygenated derivatives of omega-3 EPA and DHA that include resolvins, protectins, and maresins. Unlike standard fish oil, SPMs are central regulators of the resolution phase of inflammation, actively stimulating removal of inflammatory exudate and expediting clearance.

Key features of Thorne - Pro-Resolving Mediators include:

• Specialized pro-resolving mediators (SPMs)
• Actively resolves inflammatory response*
• Resolvins, protectins, and maresins for whole-body support*
• Different mechanism than standard omega-3s
• Third-party certified against label claims and contaminants

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Selected page contains no content. Add content to this page in the page editor.

Q: What are SPMs?
A: SPMs (Specialized Pro-Resolving Mediators) are enzymatically oxygenated derivatives of long-chain omega-3 fatty acids EPA and DHA. They include resolvins, protectins, and maresins — molecules that are central regulators of the resolution phase of inflammation.

Q: How are SPMs different from fish oil?
A: Standard fish oil provides EPA and DHA — precursors. SPMs are the pre-formed active mediators that bind specific G protein-coupled receptors to actively drive the resolution of inflammation. They stimulate removal of inflammatory exudate, expedite clearance, and support tissue restoration.

Q: Do SPMs help with wound healing?
A: Yes. SPMs stimulate wound healing and support restoration of proper tissue structure and function — beyond just resolving inflammation, they help re-establish healthy tissue state.

Q: How should I take Pro-Resolving Mediators?
A: Take 1 softgel daily or as recommended by your health-care practitioner. Contains ingredients derived from fish. Consult your practitioner if pregnant, nursing, or on medications.

Q: When would SPMs be useful?
A: Pro-Resolving Mediators are particularly relevant for individuals dealing with lingering post-exercise soreness, recovery periods, or where active resolution of inflammation is needed rather than just precursor support.

All purchases accumulate points which be can used to redeem for discounts on all items in our rewards collection. Enroll or view your current rewards balance here.

  • Earn 40 points for every $1 spent equaling 5% cash back
DESCRIPTION

Thorne Pro-Resolving Mediators delivers specialized pro-resolving mediators (SPMs) — enzymatically oxygenated derivatives of omega-3 EPA and DHA that include resolvins, protectins, and maresins. Unlike standard fish oil, SPMs are central regulators of the resolution phase of inflammation, actively stimulating removal of inflammatory exudate and expediting clearance.

Key features of Thorne - Pro-Resolving Mediators include:

• Specialized pro-resolving mediators (SPMs)
• Actively resolves inflammatory response*
• Resolvins, protectins, and maresins for whole-body support*
• Different mechanism than standard omega-3s
• Third-party certified against label claims and contaminants

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

FAQ

Q: What are SPMs?
A: SPMs (Specialized Pro-Resolving Mediators) are enzymatically oxygenated derivatives of long-chain omega-3 fatty acids EPA and DHA. They include resolvins, protectins, and maresins — molecules that are central regulators of the resolution phase of inflammation.

Q: How are SPMs different from fish oil?
A: Standard fish oil provides EPA and DHA — precursors. SPMs are the pre-formed active mediators that bind specific G protein-coupled receptors to actively drive the resolution of inflammation. They stimulate removal of inflammatory exudate, expedite clearance, and support tissue restoration.

Q: Do SPMs help with wound healing?
A: Yes. SPMs stimulate wound healing and support restoration of proper tissue structure and function — beyond just resolving inflammation, they help re-establish healthy tissue state.

Q: How should I take Pro-Resolving Mediators?
A: Take 1 softgel daily or as recommended by your health-care practitioner. Contains ingredients derived from fish. Consult your practitioner if pregnant, nursing, or on medications.

Q: When would SPMs be useful?
A: Pro-Resolving Mediators are particularly relevant for individuals dealing with lingering post-exercise soreness, recovery periods, or where active resolution of inflammation is needed rather than just precursor support.

EARN REWARDS

All purchases accumulate points which be can used to redeem for discounts on all items in our rewards collection. Enroll or view your current rewards balance here.

  • Earn 40 points for every $1 spent equaling 5% cash back
Living.Fit Rewards

Living.Fit Rewards

Learn More
Reviews by Living.Fit Customers

Testimonials

great to work with!

its so easy to work with Living.Fit, easy site navigation and prompt service

Kevin

Excellent customer service. ...

Excellent customer service. Ordered 2 sets of resistance bands, they only sent one. A simple email and they fixed it without question.

James

One stop shop!!!!

The site is my one stop shop for everything involving fitness. Easy to navigate and user friendly.

Bryan Joe

Great, affordable

Quick delivery and lots of great content

Francis

Don't think twice give it a try and be amazed

Great place to shop for quality product with a great deal.

Elizabeth

A Great Store to Purchase Gym Gear

Living.Fit offers very high-quality yet reasonably priced gym equipment. I'm very pleased with my purchase of a barbell from the shop. The item shipped quickly and was delivered without any issues. I also enjoy Living.Fit's humorous emails!

Sarah

Smooth transaction

Super smooth transaction, really couldn't ask for more!

Jon

Fast shipping and easy to use

Fast shipping, easy to use website, got me exactly what I needed

Cameron

I was very pleased with the whole purchasing process.

Purchasing the Bands through the website we smooth, communication from the company as to the status of my order was timely (I very much appreciated it:) and the Bands arrived in the expected time frame.

Leee

🛡️ Why Shop Living.Fit?

Trusted by Athletes, Trainers, and Home Gym Owners. Earn Reward Points on All Purchases

Living.Fit is a leading source for premium fitness equipment and training programs. We’ve helped over 100,000 customers upgrade their workouts—from beginners setting up their first home gym to elite athletes optimizing their performance. When you shop with us, you're backed by:


Expert-Curated Gear – We only stock equipment that meets our standards for performance, durability, and safety.

Fast, Reliable Shipping – Most orders ship within 1–3 business days from U.S. warehouses.

Real Reviews from Real Lifters – Our customer reviews are 100% verified—see what others are saying.

Top-Rated Customer Support – Questions? Our U.S.-based support team is here to help you every step of the way.

Join the Living.Fit community and experience the difference.

As Seen In

  • living fit brands logos
  • living fit brands logos
  • living fit brands logos
  • living fit brands logos