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Thorne - 5-HTP

Thorne - 5-HTP

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Overview

The serotonin levels in the body are associated with the regulation of sleep, mood, and appetite. A balanced serotonin level has been shown to support restful sleep, good mood, and decreased sugar cravings. There are several ways to support a healthy serotonin level. L-tryptophan and 5-HTP (5-Hydroxytryptophan) are both precursors to serotonin. However, supplementation with 5-HTP is preferable, because unlike L-tryptophan, 5-HTP cannot be shunted into other uses in the body, such as niacin or protein production. 5-HTP is well absorbed by the body and easily crosses the blood-brain barrier where it can increase the synthesis of serotonin in the central nervous system. And 5-HTP can be taken with meals without reducing its effectiveness.*

5-HTP (5-Hydroxytryptophan) is the intermediate metabolite the body produces when it initiates the process of converting the essential amino acid L-tryptophan to serotonin. Therefore, supplementation with 5-HTP will bypass the conversion of L-tryptophan into 5-HTP by the enzyme tryptophan hydroxylase — which is the rate-limiting step in the synthesis of serotonin — and is a conversion that can be inhibited by a number of factors, including stress, insulin resistance, increasing age, and deficiencies of vitamin C, folate, and iron. 5-HTP is well absorbed when taken orally, with about 70 percent going into the bloodstream. Intestinal absorption of 5-HTP does not require the presence of a transport molecule, and its absorption is not affected by the presence of other amino acids; therefore, 5-HTP can be taken with meals without reducing its effectiveness. 5-HTP has been shown to have a beneficial impact on mood, sleep, carbohydrate cravings, and discomfort associated with fatigue. Numerous studies of individuals with negative mood status have shown significant positive response with 50-300 mg of 5-HTP daily.*

Features

  • Serotonin Precursor: Bypasses the rate-limiting tryptophan hydroxylase step in serotonin synthesis.
  • Blood-Brain Barrier: Easily crosses the blood-brain barrier to increase serotonin synthesis in the CNS.*
  • Well Absorbed: About 70% goes into the bloodstream when taken orally.
  • Meal-Compatible: Can be taken with meals without reducing effectiveness.
  • Pyridoxal 5'-Phosphate: Contains active form of vitamin B6, the necessary cofactor for the conversion of 5-HTP to serotonin.
  • Griffonia simplicifolia: Commercially produced by extraction from the seeds of the African plant Griffonia simplicifolia.
  • Peak X-Free: Each lot thoroughly tested for contaminants, including Peak X, and is Peak X free.

How to Use

  • Suggested Use: Take 1-2 capsules three times daily or as recommended by your health-care practitioner.

Warnings

  • Allergy: Contraindicated in hypersensitivity to ingredients.
  • Pregnancy: If pregnant or nursing, do not use this product.
  • Antidepressants: 5-HTP should be used with caution in an individual currently being treated with an SSRI, MAO inhibitor, or other antidepressant medication.

The serotonin levels in the body are associated with the regulation of sleep, mood, and appetite. A balanced serotonin level has been shown to support restful sleep, good mood, and decreased sugar cravings. There are several ways to support a healthy serotonin level. L-tryptophan and 5-HTP (5-Hydroxytryptophan) are both precursors to serotonin. However, supplementation with 5-HTP is preferable, because unlike L-tryptophan, 5-HTP cannot be shunted into other uses in the body, such as niacin or protein production. 5-HTP is well absorbed by the body and easily crosses the blood-brain barrier where it can increase the synthesis of serotonin in the central nervous system. And 5-HTP can be taken with meals without reducing its effectiveness.*

5-HTP (5-Hydroxytryptophan) is the intermediate metabolite the body produces when it initiates the process of converting the essential amino acid L-tryptophan to serotonin. 5-HTP is well absorbed when taken orally, with about 70 percent going into the bloodstream. 5-HTP has been shown to have a beneficial impact on mood, sleep, carbohydrate cravings, and discomfort associated with fatigue. Numerous studies of individuals with negative mood status have shown significant positive response with 50-300 mg of 5-HTP daily.*

To further facilitate serotonin production, Thorne's 5-HTP formula contains pyridoxal 5'-phosphate, the active form of vitamin B6 and the necessary cofactor for the conversion of 5-HTP to serotonin. 5-HTP is commercially produced by extraction from the seeds of the African plant, Griffonia simplicifolia.

Each lot is thoroughly tested for contaminants, including Peak X, and is Peak X free.

Allergy Warning: This product is contraindicated in an individual with a history of hypersensitivity to any of its ingredients.

Pregnancy: If pregnant or nursing, do not use this product.

Interactions: 5-HTP should be used with caution in an individual currently being treated with an SSRI, MAO inhibitor, or other antidepressant medication.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Q: What is 5-HTP?
A: 5-HTP (5-Hydroxytryptophan) is the intermediate metabolite the body produces when converting L-tryptophan to serotonin. A serotonin precursor sourced from Griffonia simplicifolia seeds.

Q: Why 5-HTP instead of L-tryptophan?
A: Unlike L-tryptophan, 5-HTP cannot be shunted into other uses (niacin/protein). 5-HTP bypasses the tryptophan hydroxylase rate-limiting step (inhibited by stress, insulin resistance, aging, vitamin C/folate/iron deficiencies). Crosses blood-brain barrier and works with meals.

Q: What is Peak X and is this Peak X-free?
A: Peak X is a contaminant associated with some 5-HTP products. Thorne's 5-HTP is Peak X-free — each lot thoroughly tested.

Q: Can I take it with antidepressants?
A: Use with caution alongside SSRI, MAO inhibitor, or other antidepressant medications. Consult your health-care practitioner before combining.

Q: How should I take 5-HTP?
A: Take 1-2 capsules three times daily or as recommended by your health-care practitioner.

All purchases accumulate points which be can used to redeem for discounts on all items in our rewards collection. Enroll or view your current rewards balance here.

  • Earn 40 points for every $1 spent equaling 5% cash back
DESCRIPTION

The serotonin levels in the body are associated with the regulation of sleep, mood, and appetite. A balanced serotonin level has been shown to support restful sleep, good mood, and decreased sugar cravings. There are several ways to support a healthy serotonin level. L-tryptophan and 5-HTP (5-Hydroxytryptophan) are both precursors to serotonin. However, supplementation with 5-HTP is preferable, because unlike L-tryptophan, 5-HTP cannot be shunted into other uses in the body, such as niacin or protein production. 5-HTP is well absorbed by the body and easily crosses the blood-brain barrier where it can increase the synthesis of serotonin in the central nervous system. And 5-HTP can be taken with meals without reducing its effectiveness.*

5-HTP (5-Hydroxytryptophan) is the intermediate metabolite the body produces when it initiates the process of converting the essential amino acid L-tryptophan to serotonin. 5-HTP is well absorbed when taken orally, with about 70 percent going into the bloodstream. 5-HTP has been shown to have a beneficial impact on mood, sleep, carbohydrate cravings, and discomfort associated with fatigue. Numerous studies of individuals with negative mood status have shown significant positive response with 50-300 mg of 5-HTP daily.*

To further facilitate serotonin production, Thorne's 5-HTP formula contains pyridoxal 5'-phosphate, the active form of vitamin B6 and the necessary cofactor for the conversion of 5-HTP to serotonin. 5-HTP is commercially produced by extraction from the seeds of the African plant, Griffonia simplicifolia.

Each lot is thoroughly tested for contaminants, including Peak X, and is Peak X free.

Allergy Warning: This product is contraindicated in an individual with a history of hypersensitivity to any of its ingredients.

Pregnancy: If pregnant or nursing, do not use this product.

Interactions: 5-HTP should be used with caution in an individual currently being treated with an SSRI, MAO inhibitor, or other antidepressant medication.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

FAQ

Q: What is 5-HTP?
A: 5-HTP (5-Hydroxytryptophan) is the intermediate metabolite the body produces when converting L-tryptophan to serotonin. A serotonin precursor sourced from Griffonia simplicifolia seeds.

Q: Why 5-HTP instead of L-tryptophan?
A: Unlike L-tryptophan, 5-HTP cannot be shunted into other uses (niacin/protein). 5-HTP bypasses the tryptophan hydroxylase rate-limiting step (inhibited by stress, insulin resistance, aging, vitamin C/folate/iron deficiencies). Crosses blood-brain barrier and works with meals.

Q: What is Peak X and is this Peak X-free?
A: Peak X is a contaminant associated with some 5-HTP products. Thorne's 5-HTP is Peak X-free — each lot thoroughly tested.

Q: Can I take it with antidepressants?
A: Use with caution alongside SSRI, MAO inhibitor, or other antidepressant medications. Consult your health-care practitioner before combining.

Q: How should I take 5-HTP?
A: Take 1-2 capsules three times daily or as recommended by your health-care practitioner.

EARN REWARDS

All purchases accumulate points which be can used to redeem for discounts on all items in our rewards collection. Enroll or view your current rewards balance here.

  • Earn 40 points for every $1 spent equaling 5% cash back
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