{"product_id":"thorne-5-htp","title":"Thorne - 5-HTP","description":"\u003ch3\u003eOverview\u003c\/h3\u003e\u003cp\u003eThe serotonin levels in the body are associated with the regulation of sleep, mood, and appetite. A balanced serotonin level has been shown to support restful sleep, good mood, and decreased sugar cravings. There are several ways to support a healthy serotonin level. L-tryptophan and 5-HTP (5-Hydroxytryptophan) are both precursors to serotonin. However, supplementation with 5-HTP is preferable, because unlike L-tryptophan, 5-HTP cannot be shunted into other uses in the body, such as niacin or protein production. 5-HTP is well absorbed by the body and easily crosses the blood-brain barrier where it can increase the synthesis of serotonin in the central nervous system. And 5-HTP can be taken with meals without reducing its effectiveness.*\u003c\/p\u003e\u003cp\u003e5-HTP (5-Hydroxytryptophan) is the intermediate metabolite the body produces when it initiates the process of converting the essential amino acid L-tryptophan to serotonin. Therefore, supplementation with 5-HTP will bypass the conversion of L-tryptophan into 5-HTP by the enzyme tryptophan hydroxylase — which is the rate-limiting step in the synthesis of serotonin — and is a conversion that can be inhibited by a number of factors, including stress, insulin resistance, increasing age, and deficiencies of vitamin C, folate, and iron. 5-HTP is well absorbed when taken orally, with about 70 percent going into the bloodstream. Intestinal absorption of 5-HTP does not require the presence of a transport molecule, and its absorption is not affected by the presence of other amino acids; therefore, 5-HTP can be taken with meals without reducing its effectiveness. 5-HTP has been shown to have a beneficial impact on mood, sleep, carbohydrate cravings, and discomfort associated with fatigue. Numerous studies of individuals with negative mood status have shown significant positive response with 50-300 mg of 5-HTP daily.*\u003c\/p\u003e\u003ch3\u003eFeatures\u003c\/h3\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eSerotonin Precursor:\u003c\/strong\u003e Bypasses the rate-limiting tryptophan hydroxylase step in serotonin synthesis.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBlood-Brain Barrier:\u003c\/strong\u003e Easily crosses the blood-brain barrier to increase serotonin synthesis in the CNS.*\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eWell Absorbed:\u003c\/strong\u003e About 70% goes into the bloodstream when taken orally.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMeal-Compatible:\u003c\/strong\u003e Can be taken with meals without reducing effectiveness.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePyridoxal 5'-Phosphate:\u003c\/strong\u003e Contains active form of vitamin B6, the necessary cofactor for the conversion of 5-HTP to serotonin.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGriffonia simplicifolia:\u003c\/strong\u003e Commercially produced by extraction from the seeds of the African plant Griffonia simplicifolia.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePeak X-Free:\u003c\/strong\u003e Each lot thoroughly tested for contaminants, including Peak X, and is Peak X free.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch3\u003eHow to Use\u003c\/h3\u003e\u003cul\u003e\u003cli\u003e\n\u003cstrong\u003eSuggested Use:\u003c\/strong\u003e Take 1-2 capsules three times daily or as recommended by your health-care practitioner.\u003c\/li\u003e\u003c\/ul\u003e\u003ch3\u003eWarnings\u003c\/h3\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eAllergy:\u003c\/strong\u003e Contraindicated in hypersensitivity to ingredients.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePregnancy:\u003c\/strong\u003e If pregnant or nursing, do not use this product.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAntidepressants:\u003c\/strong\u003e 5-HTP should be used with caution in an individual currently being treated with an SSRI, MAO inhibitor, or other antidepressant medication.\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Thorne","offers":[{"title":"Default Title","offer_id":46547397378198,"sku":"ThorneSA503","price":39.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0508\/3670\/1334\/files\/sa503__vd9af7bad1918aceb7928aba34e5b60642bc538a1.png?v=1788211352","url":"https:\/\/www.living.fit\/products\/thorne-5-htp","provider":"Living.Fit","version":"1.0","type":"link"}